I spent a week at the St. Regis. The staff, rooms, meals, all were first class. The staff at the St Regis is GREAT, they will make your stay a pleasure. I never had any concern for anything, from the car service to and from the airport to them adding a pillow top to my bed to make it softer.
The hotel is not in a shopping district or a night club area, if you want that then stay on the other side of the river in old Shanghai, but for a great relaxing stay after work, you can't beat this place.
One last thing, check out Malones American Cafe on the other side of town for a cold beer and a great burger too.More