This morning's AnnAbor.com reports that Thanksgiving week has slowed down reservations for people coming into Ann Arbor for the Ohio State game. Normally hotels and restaurants would be 100% booked way in advance since this game is usually the weekend before Thanksgiving. That makes me think the ticket prices for the game (which are usually astronomical through resale venues) are lower than normal too (not to say they'll be cheap).
There are still hotels available and the typical restaurants for pre and post game festivities still have reservations open. Check out this story if you're thinking this might be a fun way to spend a day of your Thanksgiving weekend: