There is not very big difference during the main season.
General advice to be out of crowds ( it works sometimes):
Charles Bridge - early morning (before 9,30 - 10 am).
The Old Town - morning time, before 11 am.
Don´t walk just the main streets ( Karlova, Nerudova ) and you can find the quiet places also during the day.
Have a nice stay in Prague!
don't worry about stag crowds ,they are few and far between theses days.
Tourist crownds can be quite daunting and following Hana;s hekp will make things a bit bettermunfortunetly with Prague being such a popular toursit destination you really can't avoid the crowds.
helpful guidelines from Hana
at the same time, of course, there are so many lovely parts of Prague that tourists don't go to and thus they are not crowded
As Hana says, Karlova and Nerudova can be a complete nightmare in the middle of the day -- those streets are best early or late
Thank you all for the helpful responses.
you're welcome, hope you have a great time in this wonderful city
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