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Domilise's Po-Boys

5240 Annunciation St, New Orleans, LA 70115-1848
+1 504-899-9126
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  • Excellent62%
  • Very good22%
  • Average10%
  • Poor2%
  • Terrible2%
Travellers talk about
“roast beef” (37 reviews)
“shrimp po boy” (29 reviews)
“sandwich” (47 reviews)
Open Now
All hours
American, Seafood, Cajun & Creole
5240 Annunciation St, New Orleans, LA 70115-1848
Neighbourhood: Uptown / Carrollton
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Reviews (267)
Traveller rating
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1 - 10 of 267 reviews

Reviewed 5 days ago

Great local spot with cool people and a to die for po-boy! Don't miss this quintessential spot! It is the best in NOLA

Thank doratheexplorer430
Reviewed 2 weeks ago

It could only happen in NOLA; breakfast at Domilese's before heading for the Jazz Fest. We got there around 10am (opening time) for a fried oyster po-boy and Abita Amber. There was only one other couple there, so we had the place to ourselves. The...More

Thank boudin
Reviewed 3 weeks ago via mobile

A great gem off the beaten path. I had the shrimp/oyster combo and it was excellent. Service was awesome. Seating is very limited but all part of the experience.

Thank jmdeans
Reviewed 4 weeks ago via mobile

My wife and I stopped by for a late lunch yesterday... this was only our 2nd time to eat there with our first being the year after Katrina... the food was as good as we remember but what caught my attention this time around were...More

1  Thank jerseytraveller_8
Reviewed 4 weeks ago

We popped in about 30 minutes before closing, and there was no wait at all. My daughter and I got the shrimp po-boy and my husband got the oyster po-boy. We all loved it. The fries were delicious and crispy and the po-boys were done...More

Thank hippiefrog
Reviewed 4 weeks ago via mobile

First time visiting, we ordered a catfish/shrimp Po boy dressed, so so good! Our kids ordered the roast beef, meatball and burger, not a bite was left! Take a number when you enter, each order is taken and made with TLC, enjoy with a local...More

Thank Route12N
Reviewed 5 weeks ago

I define this place as a "Must-Eat" restaurant in NOLA. If you visit, please stop by Domilise's and grab a fried-shrimp po-boy! You won't regret it. Seating is an issue at this place and you will wait to eat... but it's totally worth it for...More

Thank jwat1776
Reviewed 10 April 2017

My favorite is the roast beef with swiss cheese melted and dressed. For 48 years I have been going there. The shrimp poboy is awesome with a little kick of hot sauce. After many years of traveling this is my favorite sandwich place.

Thank arthur r
Reviewed 6 April 2017 via mobile

The best Po Boy I have ever eaten. Trip advisor had it closed on Thursday, but it isn't. The only day it is closed is Sunday. This will be a stop when in New Orleans.

Thank Gary C
Reviewed 3 April 2017

Friends tipped me off that if I wanted the authentic New Orleans Po-Boy, Domilise's is the place. They were not wrong. We shared the large half-and-half, (shrimp and oysters.) As if this place needs another five star review. Had a good time talking with the...More

Thank SC5100
Uptown / Carrollton
Very much their own self sufficient unit within the
greater metro area, Uptown and Carrollton tone down
the urban edge with a friendly attitude and collegiate
feel. Home to Tulane and Loyola Universities, all the
students living in the area ensure that Uptown and
Carrollton stay youthful, cosmopolitan and vibrantly
fun. Two of the liveliest thoroughfares for nightlife
and socializing (and yes of course more of the city’s
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Questions & AnswersAsk a question
Ron B
How do you get use to a place that is in this condition? How could anyone enjoy eating a meal in surrounding like this?
1 August 2015|
Answer Show all 3 answers
Response from Ed M | Reviewed this property |
I am not sure what condition you mean. The place has been around for about a century but it is clean and the food is delicious. Maybe this type of place is just not for you.
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Restaurant Details

Rating summary
  • Food
  • Value
Lunch, Dinner
Restaurant features
Takeout, Seating, Wheelchair Accessible, Serves Alcohol
Good for
Child-friendly, Kids, Local cuisine
Open Hours
10:00 - 19:00
10:00 - 19:00
10:00 - 19:00
10:00 - 19:00
10:00 - 19:00
10:00 - 19:00
Location and Contact Information
  • Address: 5240 Annunciation St, New Orleans, LA 70115-1848
  • Location: United States  >  Louisiana (LA)  >  New Orleans>  > Uptown / Carrollton
  • Neighbourhood: Uptown / Carrollton
  • Phone Number: +1 504-899-9126
  • E-mail