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Rx Restaurant and Bar

Certificate of Excellence
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421 Castle St, Wilmington, NC 28401-5141
+1 910-399-3080
17:00 - 22:30
Closed now
See all hours
Sun 10:00 - 22:00
Tue - Thu 17:00 - 22:00
Fri - Sat 17:00 - 22:30
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203 Reviews from our TripAdvisor Community

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Time of year
Showing 202: English reviews
Cary, North Carolina
Level Contributor
39 reviews
34 restaurant reviews
common_n_restaurant_reviews_1bd8 4 helpful votes
Reviewed 1 week ago NEW via mobile

Knowing it was Mother's Day we knew restaurants would be busy so we had a reservation for this highly rated restaurant. It was going to be our first time at Rx. Walked over from around front street, which in itself was very interesting due to the many large old houses that line some of the streets Now, back to Rx.... More 

Thank mannart03
Raleigh, North Carolina
Level Contributor
56 reviews
33 restaurant reviews
common_n_restaurant_reviews_1bd8 12 helpful votes
Reviewed 2 weeks ago

We finally tried Rx last night with friends. The food was fabulous! The fried green tomatoes with pimento cheese and bacon jam were fabulous. I had the pork chop - tender and moist. My husband's shrimp and grits were some of the best he has ever had. Great wine list as well. Our server was Rich and had did a... More 

Thank Sam18Wil
Eastern NC
Level Contributor
45 reviews
28 restaurant reviews
common_n_restaurant_reviews_1bd8 18 helpful votes
Reviewed 2 weeks ago via mobile

Had a late reservation on a Saturday night for dinner. The restaurant wasn't very crowded and our service was attentive and warm. We started with drink specials which were solid. The heirloom tomato salad was incredible and have since tried to replicate it at home but to no avail. I had the duck breast entree and my hubby had the... More 

Thank easternNCgirl
Charlotte, North Carolina
Level Contributor
69 reviews
47 restaurant reviews
common_n_restaurant_reviews_1bd8 4 helpful votes
Reviewed 14 April 2017

A friend's friend recommended we all meet there for Sunday Brunch. I googled the menu and found some strange sounding menu items. Once there, it was a quaint place with pleasant surprises. Pork belly was bacon, for example. The mini biscuits were excellent! The way they did shrimp and grits was outstanding. The server was attentive and cheery without being... More 

Thank Andra' E
Level Contributor
55 reviews
24 restaurant reviews
common_n_restaurant_reviews_1bd8 14 helpful votes
Reviewed 12 March 2017 via mobile

We had brunch and the food was really good. My french toast topped with blueberries was wonderful! Great variety of food on the menu - sure to please everyone in your group! Nice atmosphere and good service as well.

Thank TravelerKay
Tryon, North Carolina
Level Contributor
60 reviews
48 restaurant reviews
common_n_restaurant_reviews_1bd8 34 helpful votes
Reviewed 11 March 2017

Our first visit to Rx Restaurant and Bar. It was a weekday evening and the place was pretty busy, even at our 8:00pm reservation time. Friendly and caring staff, they went above and beyond to make our experience the best they could. The wine list is varied, something for every palate and price point, supplemented by excellent and knowledgeable advice... More 

1 Thank Roger S
Wilmington, NC
Level Contributor
20 reviews
15 restaurant reviews
common_n_restaurant_reviews_1bd8 17 helpful votes
Reviewed 6 March 2017

Make sure to get a reservation. Delicious food, perfectly prepared. Nice size portions. Only negative is the decor

Thank happyWilmington_NC
Leland, North Carolina
Level Contributor
216 reviews
133 restaurant reviews
common_n_restaurant_reviews_1bd8 44 helpful votes
Reviewed 22 January 2017 via mobile

Recently went here with visiting family members without knowing anything about the restaurant. We were not disappointed. They have a new menu every night, including interesting cocktail options. The night we were there they had five entree options with a variety of ingredients. Nice, comfortable neighborhood feel with cozy bar. Pleasant service.

Thank NCTravelfan58
Level Contributor
52 reviews
26 restaurant reviews
common_n_restaurant_reviews_1bd8 35 helpful votes
Reviewed 3 January 2017

Being new to Wilmington we had heard rave reviews of Rx Restaurant and Bar. Being a fan of local farm to table and fresh ingredients we were excited to find this restaurant. We decided to try it for New Years Eve. Usually not a great night for restaurants since they are usually very busy and quality sometimes is lacking.....Well, let... More 

Thank Floridawillsgirl
Vienna, Virginia
Level Contributor
17 reviews
13 restaurant reviews
common_n_restaurant_reviews_1bd8 12 helpful votes
Reviewed 3 January 2017

Meal was very good.... Table choices included the two layer chicken and fish. Service was very good and accommodating as we worked through the wine selections... Definitely order the pig ears as an appetizer. If you are visitng Wilmington this is a not to be missed restaurant

Thank Ecanv

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Restaurant Details

Rating summary
  • Food
  • Value
Average prices
US$30 - US$30
American, Gluten Free Options, Vegetarian Friendly
Lunch, Dinner, Brunch, After-hours
Restaurant features
Reservations, Seating, Waitstaff, Serves Alcohol, Full Bar, Wheelchair Accessible
Dining Style
Casual Elegant
Good for
Local cuisine, Romantic, Child-friendly, Special Occasion Dining, Bar Scene
Open Hours
10:00 - 22:00
17:00 - 22:00
17:00 - 22:00
17:00 - 22:00
17:00 - 22:30
17:00 - 22:30
Location and Contact Information
  • Address: 421 Castle St, Wilmington, NC 28401-5141
  • Location: United States  >  North Carolina (NC)  >  North Carolina Coast  >  Wilmington
  • Phone Number: +1 910-399-3080
Located in the old Hall's Drugstore on 5th and Castle

Questions & Answers

Here's what previous visitors have asked, with answers from representatives of Rx Restaurant and Bar and other visitors
2 questions
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Kingsport, Tennessee, United States
over a year ago
Kingsport, Tennessee, United States
over a year ago

See all questions (2)

Questions? Get answers from Rx Restaurant and Bar staff and past visitors.
Posting guidelines
Typical questions asked:
  • Do you have gluten-free options?
  • Is there a dress code?
  • Do you allow dogs on the outdoor patio?