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Panacea Coffeehouse Cafe & Roastery

66 Commerce St, Waynesville, NC 28786-5738
+1 828-452-6200
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  • Excellent64%
  • Very good28%
  • Average6%
  • Poor1%
  • Terrible1%
Travellers talk about
“panini” (18 reviews)
“sandwiches” (33 reviews)
“lox” (4 reviews)
Open Now
07:00 - 17:00All hours
American, Cafe, International, Healthy, Vegetarian Friendly, Vegan Options, Gluten Free Options
€€ - €€€
66 Commerce St, Waynesville, NC 28786-5738
All Details
Write a ReviewReviews (223)
Traveller rating
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Time of year

1 - 10 of 223 reviews

Reviewed 6 days ago

Loved my chai latte and coffee here. They showcase local artists each month, have an awesome outdoor area by the river, and a cozy-yet-industrial vibe inside. Smells amazing, too, since they roast the beans right out in the open for everyone to enjoy!

Thank Katelan F
Reviewed 3 weeks ago via mobile

Always has a great special menu for beverage and daily entrees... Their soups and sandwiches are delicious! It’s a must to start your day when visiting the town of Waynesville , NC.

Thank Marcela P
Reviewed 1 December 2017

The seating outside overlooks a brook. Very pleasant and inviting. I hear it gets very busy during the summer months probably because of the outside seating. Still pleasant in November! They offer a great Monte Cristo sandwich.

Thank Serena414
Reviewed 27 November 2017 via mobile

Stopped in for a coffee and hot chocolate for my daughter so I'm rating based more on service and atmosphere than food. Although I got a slice of quiche which was good and it was served with a bowl of fresh fruit slices. They had...More

Thank Mequel F
Reviewed 11 November 2017 via mobile

I always enjoy coming to this coffee shop, especially when their roaster is actively roasting coffee. Their coffee is great and they have a great casual atmosphere whether you want to sit at a table or on a couch. Everyone is extremely nice.

Thank Prvteye
Reviewed 7 November 2017

They have the best sandwiches and salads. We have eaten several time outside by the river and it is lovely. Everything Ive eaten there is great. A must try.

Thank nwithner
Reviewed 28 October 2017

A roomy restaurant with inside and outside seating and a college coffee house vibe. The paninis are served with grapes and pretzels. The aroma of coffee permeates the restaurant. Sofas, tables and chairs, and Wifi invite people to stay. The outside tables overlook a small...More

Thank Joni M F
Reviewed 22 October 2017 via mobile

A must stop when I’m in the area is to Panacea Coffeehouse. My cappuccino was spot on as usual. Great atmosphere inside and out back. We had fun playing with a kitty. She was black with beautiful green cat eyes. Just in time for Halloween....More

Thank tastebudtravelers
Reviewed 8 October 2017

Lovely cafe’ with good coffee but the quich was microwaved and chewy. Didn’t try the pastries but will not return.

Thank Tami O
Reviewed 3 October 2017

The Coffeehouse is nestled in the unsuspecting warehouse area of Waynesville next to the train tracks. Panacea completely gutted the warehouse into a neat, hip, coffee roastery with great food and coffee. The back porch area sits right on a beautiful creek and is lit...More

Thank pittmanarizona
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Restaurant Details

Rating summary
  • Food
  • Value
Average prices
US$5 - US$12
Breakfast, Lunch, Brunch
Restaurant features
Takeout, Outdoor Seating, Seating, Wheelchair Accessible, Free Wifi
Good for
Child-friendly, Business meetings, Kids
Open Hours
07:00 - 17:00
07:00 - 17:00
07:00 - 17:00
07:00 - 17:00
07:00 - 17:00
08:00 - 17:00
Location and Contact Information
  • Address: 66 Commerce St, Waynesville, NC 28786-5738
  • Location: United States  >  North Carolina (NC)  >  North Carolina Mountains  >  Waynesville
  • Phone Number: +1 828-452-6200
  • E-mail
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