We noticed that you're using an unsupported browser. The TripAdvisor website may not display properly.We support the following browsers:
Windows: Internet Explorer, Mozilla Firefox, Google Chrome. Mac: Safari.
View map
Sponsored by:
Clear all
Your Selections
  Free Wifi Budget Breakfast included Pool Mid-range Free Parking Family-friendly Charming Quiet Pets Allowed Suites Kitchenette Fitness centre Room Service Business Internet & up & up Non-Smoking Hotel Business Centre Air Conditioning & up Meeting Rooms Independent Hotels Accessible rooms Drury Inn & Suites Super 8 Cheap Hotels Hotels with Smoking Rooms €€ €€€ €€€€ Pear Tree Inn Quality Inn Holiday Inn Express Comfort Inn Concierge Hotels with Military Discounts Drury Plaza Hotel Foodie Restaurant Like a Local Candlewood Suites Hampton Inn Comfort Suites Best Western Plus Days Inn Motel 6 Americas Best Value Inns Beach Goer Red Lion Hotels Spring Break Hotels Family Holiday Maker Within 10 km Within 25 km Within 50 km Any distance from Osage Centre
Price per night
Enter dates & see best prices
to
Amenities
More
Amenities
Location
(reset)
Any Distance
from
Traveller Rating
Hotel class
Style
More
Style
Hotel brand
More
Hotel brand
  • Sort by:
  • Traveller Ranked
  • Best Value
  • Lowest Price
  • Distance
TripAdvisor members only.
Login for exclusive access to hotel deals up to 40% off
Login to get best prices
Like saving money? We search up to 200 sites to help you save up to 30%
Super 8 Cape Girardeau
Priceline
US$73
View Deal
2011 N Kingshighway St, I-55 exit #99, Cape Girardeau, MO 63701-2127
1.4 km from Osage Centre
  • Free Wifi
  • Free Parking
Town House Inn Cape Girardeau
Booking.com
US$76
View Deal
505 N Kingshighway St, Cape Girardeau, MO 63701-4333
2.2 km from Osage Centre
  • Free Wifi
  • Free Parking
Drury Plaza Hotel Cape Girardeau Conference Center
Booking.com
US$193
View Deal
3351 Percy Drive, Cape Girardeau, MO 63701
2.8 km from Osage Centre
  • Breakfast included
  • Pool
Pear Tree Inn Cape Girardeau Near the Medical Center
Booking.com
View Deal
3248 William St, Cape Girardeau, MO 63703-4960
3.0 km from Osage Centre
  • Free Wifi
  • Free Parking
Holiday Inn Express Cape Girardeau
HIExpress.com
US$147
View Deal
3253 William St, Cape Girardeau, MO 63703-4961
3.3 km from Osage Centre
  • Free Wifi
  • Free Parking
Auburn Place Hotel & Suites
Booking.com
View Deal
3265 William St, Cape Girardeau, MO 63703-4961
3.3 km from Osage Centre
  • Free Wifi
  • Free Parking
Hampton Inn Cape Girardeau I-55 East
SAVE US$17
US$151
Priceline
US$134
View Deal
207 S Mount Auburn Rd, Cape Girardeau, MO 63703-4912
3.4 km from Osage Centre
  • Free Wifi
  • Free Parking
Drury Inn & Suites Cape Girardeau
Expedia.com
View Deal
3303 Campster Dr, Cape Girardeau, MO 63701-8472
3.4 km from Osage Centre
  • Free Wifi
  • Free Parking
Pear Tree Inn Cape Girardeau West
Booking.com
US$101
View Deal
103 Cape West Pkwy, Cape Girardeau, MO 63701-8418
3.4 km from Osage Centre
  • Free Wifi
  • Free Parking
Comfort Suites Jackson/Cape Girardeau
Booking.com
US$75
View Deal
2904 Old Orchard Rd, Jackson, MO 63755-3830
4.6 km from Osage Centre
  • Free Wifi
  • Free Parking
Candlewood Suites Cape Girardeau
SAVE US$12
US$123
Priceline
US$111
View Deal
485 S Mount Auburn Rd, Cape Girardeau, MO 63703-4926
4.6 km from Osage Centre
  • Free Wifi
  • Free Parking
Town House Inn
Expedia.com
US$107
View Deal
517 E Jackson Blvd, Jackson, MO 63755-2425
9.8 km from Osage Centre
  • Free Wifi
  • Free Parking
No photo provided
517 Highway 61 East, Jackson, MO 63755
9.8 km from Osage Centre
  • Restaurant
  • Fitness centre
Drury Inn & Suites Jackson, MO
Booking.com
US$121
View Deal
225 Drury Ln, Jackson, MO 63755-6807
12.7 km from Osage Centre
  • Free Wifi
  • Free Parking
Americas Best Value Inn - Ullin/Mounds
Booking.com
US$70
View Deal
128 Cheekwood Ln, Ullin, IL 62992-2145
36.7 km from Osage Centre
  • Free Wifi
  • Free Parking
Quality Inn Cairo Mounds
Expedia.com
US$70
View Deal
13201 Kessler Rd, I 57 & Rt 3, Cairo, IL 62914-3101
46.0 km from Osage Centre
  • Free Wifi
  • Free Parking
Drury Inn & Suites Sikeston
Travelocity
View Deal
2608 E Malone Ave, Sikeston, MO 63801-5318
48.7 km from Osage Centre
  • Free Wifi
  • Free Parking
Pear Tree Inn Sikeston
Booking.com
View Deal
2602 E Malone Ave, Sikeston, MO 63801-5318
48.8 km from Osage Centre
  • Free Wifi
  • Free Parking
Motel 6 Sikeston
Booking.com
View Deal
110 S Interstate Dr, I-55 at US-62/East Malone Street, Exit #67, Sikeston, MO 63801-8641
48.8 km from Osage Centre
  • Free Wifi
  • Free Parking
Best Western Plus Sikeston
Priceline
View Deal
120 S Interstate Dr, Sikeston, MO 63801-8641
48.9 km from Osage Centre
  • Free Wifi
  • Free Parking
Super 8 Sikeston/Miner Area
Priceline
View Deal
2609 E Malone Ave, I-55 Exit 67, Sikeston, MO 63801-5317
48.9 km from Osage Centre
  • Free Wifi
  • Free Parking
Comfort Inn & Suites Sikeston
Travelocity
View Deal
109 Matthews Ln, Sikeston, MO 63801-5319
49.0 km from Osage Centre
  • Free Wifi
  • Free Parking
Country Hearth Inn - Sikeston
Travelocity
View Deal
100 Matthews Ln, Sikeston, MO 63801-5320
49.0 km from Osage Centre
  • Free Wifi
  • Free Parking
Americas Best Value Inn & Suites Sikeston MO
Expedia.com
View Deal
220 S Interstate Dr, Sikeston, MO 63801-8642
49.2 km from Osage Centre
  • Free Wifi
  • Free Parking
Eagle Inn
SAVE US$4
US$56
Hotels.com
US$52
View Deal
2811 E Marshall St, Highway 60 & 62 East, Charleston, MO 63834-9321
50.4 km from Osage Centre
  • Free Wifi
Super 8 Charleston MO
Expedia.com
US$58
View Deal
310 S Story St, Charleston, MO 63834-8118
50.6 km from Osage Centre
  • Free Wifi
  • Free Parking
Quality Inn
SAVE US$17
US$84
Expedia.com
US$67
View Deal
102 Drake St, I-57 ex. 10, Charleston, MO 63834-4304
50.7 km from Osage Centre
  • Free Wifi
  • Free Parking
Savings alert: 14% below average rate

The price you found is 14% lower than this hotel's average rate of US$78/night.

We analyze rates over a 60 day period, and compare your selection to the average rate of comparable stays to ensure you're getting the best possible deal.

No photo provided
U.S. Hwy 51, Rt. 2, Cairo, IL 62914
50.7 km from Osage Centre
    Holiday Inn Express & Suites Sikeston
    HIExpress.com
    US$130
    View Deal
    115 Hospitality Dr, Sikeston, MO 63801-9304
    52.5 km from Osage Centre
    • Free Wifi
    • Free Parking
    Days Inn Sikeston
    Booking.com
    View Deal
    1330 S Main St, Sikeston, MO 63801-9359
    52.6 km from Osage Centre
    • Free Wifi
    • Free Parking
    Still looking for a place to stay?
    Cape Girardeau has 3 B&Bs/inns with 105 reviews
    Neumeyer's Bed and Breakfast
    25 S Lorimier St, Cape Girardeau, MO 63703-7415
    5.1 km from Osage Centre
    • Free Parking
    • Free Internet
    Bellevue Bed and Breakfast
    312 Bellevue St, Cape Girardeau, MO 63701-7233
    4.9 km from Osage Centre
    • Free Wifi
    • Free Parking
    No photo provided
    536 Broadway St, Cape Girardeau, MO 63701-5605
    4.6 km from Osage Centre
      See all 3 Cape Girardeau B&Bs/inns
      See all hotels in or near Cape Girardeau
      Comfort Suites Jackson/Cape Girardeau
      Booking.com
      US$75
      View Deal
      2904 Old Orchard Rd, Jackson, MO 63755-3830
      4.6 km from Osage Centre
      • Free Wifi
      • Free Parking
      Town House Inn
      Expedia.com
      US$107
      View Deal
      517 E Jackson Blvd, Jackson, MO 63755-2425
      9.8 km from Osage Centre
      • Free Wifi
      • Free Parking
      Drury Inn & Suites Jackson, MO
      Booking.com
      US$121
      View Deal
      225 Drury Ln, Jackson, MO 63755-6807
      12.7 km from Osage Centre
      • Free Wifi
      • Free Parking
      Americas Best Value Inn - Ullin/Mounds
      Booking.com
      US$70
      View Deal
      128 Cheekwood Ln, Ullin, IL 62992-2145
      36.7 km from Osage Centre
      • Free Wifi
      • Free Parking
      Quality Inn Cairo Mounds
      Expedia.com
      US$70
      View Deal
      13201 Kessler Rd, I 57 & Rt 3, Cairo, IL 62914-3101
      46.0 km from Osage Centre
      • Free Wifi
      • Free Parking
      *Prices are provided by our partners, and reflect average nightly room rates, including taxes and fees that are fixed, known to our partners, and due at time of booking. Please see our partners for more details.