One of the most popular resort towns on the Italian Riviera, little Portofino has just over 500 permanent residents. But that all changes on summer days when the sun is shining and the yachting set drops anchor in the harbor to wander about. Boutiques, art galleries, cafes and restaurants line the tiny streets. Diving, hiking and beach-going are popular local pastimes, and there are even some historic sights like the Church of St. Martin (Divo Martino) and the Castello Brown hilltop fortress.

Wandering the narrow caruggi alleyways of Genoa is a bit like solving a medieval labyrinth. In the heart of the Italian port city lies Piazza de Ferrari, a main square with a beautiful fountain and a perimeter lined with historic buildings, including the Palace of the Doges the Teatro Carlo Felice, which was destroyed during WWII and subsequently rebuilt. The seaside neighborhood of Boccadasse is vision of pink and yellow buildings that brighten up this lovely fishing village.

San Gimignano, known as the "city of beautiful towers," had 72 towers in its heyday. Now 14 remain, and, rising above Tuscany's Elsa Valley, they make the town look like a mediaeval dreamscape. Take in the fresco-covered Collegiate Church, the Civic Museum and the views from atop 177-foot Torre Grossa. Daytrippers from Florence tend to fill up the streets during the day, so for a more up-close-and-personal look at the town, spend the night.

Nearly crossing northern Italy from the Adriatic Sea westward, Emilia-Romagna gets its name from Via Emilia, the Rimini-to-Piacenza ancient Roman road it straddles. With a rich mix of age-old agriculture and modern industry, the region is home to many historic and cultural gems, both in its larger towns like Bologna, Modena and Ravenna, as well as in its many small hilltop villages. Of course, the region’s best offerings also include native culinary wonders like parmigiano cheese and tortellini.

Amsterdam is truly a biker’s city, although pedaling along the labyrinthine streets can get a little chaotic. Stick to walking and you won’t be disappointed. The gentle canals make a perfect backdrop for exploring the Jordaan and Rembrandtplein square. Pop into the Red Light District if you must—if only so you can say you’ve been there. The Anne Frank House is one of the most moving experiences a traveller can have, and the Van Gogh Museum boasts a sensational collection of works.

From Shoreditch’s swaggering style to Camden’s punky vibe and chic Portobello Road, London is many worlds in one. The city’s energy means that no two days are the same. Explore royal or historic sites, tick off landmarks from your bucket list, eat and drink in exclusive Michelin-starred restaurants, enjoy a pint in a traditional pub, or get lost down winding cobbled streets and see what you stumble across – when it comes to London, the possibilities are endless.

You've probably heard that Guinness tastes better in Dublin (fresh from the factory), but what you may not know is that Dublin is a perfect destination for the whole family. No, we're not suggesting you let the kiddies drink a pint. Instead, take them to the Dublin Zoo, to feed the ducks in Stephen's Green or on a picnic in Phoenix Park. Scholars enjoy walking in the literary footsteps of such writers as Yeats and Joyce, while discerning shoppers have their pick of designer boutiques.

"The City of Tribes" provides a fun blast of the Ireland many first-time visitors expect. The compact city centre, with its winding streets, packed pubs and air of celebration, is easily walked - or pubcrawled. The west-coast city of almost 70,000 is home to merry bands of students, artists, writers and craftspeople, and is merriest during summer's Galway's Arts Festival. Don't miss shopping for Claddagh rings, the Druid Theatre or having a pint o' the black stuff at the atmospheric Tigh Neachtain pub.

Strongly influenced by the tribal culture of the Guanches (the original inhabitants), Tenerife was conquered by the Spanish 500 years ago. It's home to Mount Teide, Spain's tallest peak, and to the popular beach resort of Los Gigantes. Today visitors flock to Loro Park to see tropical birds, to Tenerife Zoo Monkey Park and to Parque Nacional Las Canadas del Teide's volcanic rock formations. Explore by car or with a "bono bus" ticket, which offers reductions on regular prices.