Casinos, naturally, continue to draw tourists to Las Vegas. From penny slots to high-stakes table games in private salons, you'll find it here. But there's much more to Las Vegas than gambling. Our weekend itinerary highlights attractions of a different sort, from the choreographed fountains at the Bellagio to the Liberace Museum. Las Vegas is also surprisingly family-friendly. In an attempt to appeal to kids, the hotels have spent millions developing technically sophisticated indoor amusement rides such as the Race for Atlantis.

You'll find crashing waves off Cabo's Pacific coast and sheltered, calm water on the Sea of Cortez. Given those options, Cabo has built a rare reputation for both excellent outdoor sports (big-game fishing, diving and kayaking, among others) and pure beach relaxation. Of course, there's also great nightlife. Cabo’s resorts, hotels and inns cater to everyone from honeymooners to families to Hollywood stars seeking a weekend getaway.

Tulum lies south of Playa del Carmen, with lush, bougainvillea-filled jungle at its back. The town of 10,000 is divided into three separate sections, the Mayan ruins, the hotel zone and the pueblo. Popular with tour buses from Cancun, the ruins, some of the best preserved in the Yucatan, perch on cliffs along the coast. Those staying in Tulum can easily bike around, or explore swimming opportunities off white sand beaches and in subterranean sinkholes. The clear Caribbean waters also offer great diving.

It’s not just for spring-breakers. Cancun, with its golden beaches and perfect climate, is the premiere coastal destination in Mexico. And while there is certainly a 365-day party available for college students, resorts cater well to families and to those seeking solitude. This Yucatan paradise is also the gateway to the ruins of Tulum and Chichén Itzá.

Isla Mujeres offers a wide variety of tempting options for beach lovers, and is a relative bargain. Snorkel with tropical fish amid coral reefs, skim the blue waters by kayak or boat, or windsurf along the shores of soft, sandy beaches. On land, you can sunbathe, dine on seafood, dance to Latin rhythms, tour on a moped or belly up to the bar for fresh, delicious drinks.

From the Magic Kingdom to magical spa treatments, Orlando sparkles with the promise of adventure. Spend a day exploring the world-famous Disney theme parks or screaming your head off on a Universal Studios roller coaster. For a less adrenaline-pumping afternoon, enjoy the quiet natural beauty of the Harry P. Leu Gardens or enjoy a seaweed scrub at a luxury day spa. Savor fresh and local ingredients at one of Orlando’s James Beard-nominated restaurants.

The antidote to homogenized culture, the Caribbean's largest city is one of charm and contradictions. The restored Spanish Colonial Habana Vieja contrasts with the faded grandeur and dilapidation in much of the rest of the city. Five centuries of architectural heritage, cobbled streets, palms swaying in a tropical breeze, and an all-round beguiling ambiance, all combine to make an irresistible destination. Don't miss verdant Vedado, a laid-back neighborhood of cultural institutions, restaurants and bars.

Cuba's top beach destination sits on a 13-mile-long peninsula with powder soft sands lapped by waters of the Kawama Channel. Resort hotels teem along the shore that U.S. celebrities and gangsters, including Capone, discovered in the 1920s. Clubs and bars provide mojitos and merriment, after long days baking on the beach, golfing, diving or deep sea fishing. Rent a scooter or hop aboard an open-air tourist train or bus to see more of this stunning spot. Caves, keys and virgin forest add to the area's allure.