Welcome to the Holiday Inn Express San Antonio Medical Center/Crossroads, the cultural gateway to the Southwest and a popular tourist destination. The Holiday Inn Express & Suites is conveniently located only 5.5 miles west of the Alamo and the River Walk in downtown San Antonio and 3 miles east of the South Texas Medical Center. The premier location of San Antonio s newest hotel is perfectly accessible to all area attractions and businesses: TexSan Heart Hospital, CTRC-Cancer Therapy & Research Center, Christas Santa Rosa Health Care, UT Health Center, Verizon, Toyota, Bank of America, and Wachovia are just a few of the companies that call San Antonio home. The city has a strong military presence as well it is home to Fort Sam Houston, Lackland Air Force Base, Randolph Air Force Base, and Brooks City-Base. The hotel is centrally located in San Antonio just minutes from Six Flags Fiesta Texas, SeaWorld San Antonio, Splashtown Water Park, the Historic Missions, Breckenridge Park, the Alamodome, AT&T Center where the successful San Antonio Spurs play basketball, and the Marion Koogler McNay Art Museum. Guests of the Holiday Inn Express & Suites San Antonio stay connected with our complimentary high-speed wired & wireless Internet access throughout the hotel, relax in our outdoor pool and spa, or work out in our well-equipped fitness center.