Stay Smart at our Holiday Inn Express and Suites Ironton. Experience a memorable stay with first class amenities and beautiful decor. Located off Hwy US 52, behind the new Frisches Big Boy, our Holiday Inn Express and Suites Ironton hotel is brand new and located in the southeast tri state region of Ohio. Proudly serving the communities of Huntington, WV and Ashland, KY, the hotel is only minutes from major businesses in the area such as Ashland Chemical Company and Sunoco Chemical plants. The Holiday Inn Express and Suites Ironton provides a name you can trust at a price you can afford, making us the place where you can Stay Smart. Our hotel knows what corporate travelers want. We are conveniently situated within easy driving distance of downtown Huntington and other major businesses, including Marathon Petroleum, AK Steel, Haverhill Chemical and the Liebert Corporation. Complimentary high speed Internet access, a 24 hr Business Center and 1000 square feet of flexible meeting space.