With your guide and group, start the tour with a walk into the heart of the Jewish Ghetto. Originating in the 16th century, the enclave is enshrined in Roman culture and is home to landmarks, such as the Colosseum-like Theatre of Marcellus (Teatro Marcello).
Swing past the Mouth of Truth (Bocca della Verita), a face-like plaque that’s rumored to bite the hands of liars. Then, pause by Circus Maximus before you continue to the ancient Appian Way. Once the busiest road into Rome, the street is steeped in history. Hear tales of emperors and Spartacus, as you amble along the cobbles and pass into Aqueduct Park. Gaze into the Baths of Caracalla and strike a pose for photos from Janiculum Hill—it’s one of the best city vantage points.
Take in other highlights, such as a so-called optical illusion of St. Peter’s Basilica and Rome’s only pyramid. Then, work your way back to central Rome.