Hotels location is perfect for shopping and sightseeing, everything important is in a walking distance. The standard room was clean, nice and well equipped, but small - we had problems with placing of the second suitcase. The personnel at the reception were very very helpful and friendly, unlike the restaurant staff during breakfast. Breakfast was also ok, but its diversity... More

My husband and I spent 4 nights here in December and absolutely loved it. The rooms are not very big, but are modern and kept very clean. The breakfast offered is very limited but sufficient. The location we found was amazing, we walked literally everywhere to the Trevi Fountain, the Spanish steps, the Vatican, the Sistine chapel and the Pantheon,... More

This was our first trip to Rome. We choose to stay at the twenty one hotel mainly because it looked new, it was not very centrally located (10 mins walk) and the price was also good. The hotel is value for money. It is located on Via cola di Rienzo which has several nice shops and restaurants. The only disadvantage... More

We stayed 4 nights at this hotel - room was extremely small. We had 2 small suitcases and could not walk around the bed since the only place for the suitcases was on the floor by the bed. The room was not soundproff - we could hear the next door rooms door open and close late at night. When we... More

Good location for sightseeing as could walk to most of key sights or to tour-bus pick-up points. Would recommend the trolley tour bus, as can hop on and off at key locations. Hotel room very modern and clean, but strangely dark. Breakfast adequate if you like cold meats and cheese. Bar staff very attentive and helpful. More

My brother and I had a great stay here. Room small but clean, breakfast had variety and quality. However, we watched two films on Sky, both were quoted on-screen as costing €2.50. On checkout we were charged €10 euro per film. We had no doubt the hotel were fully aware of this scam so just be warned. More

Just arrived today from a 4 day trip to Rome. I went about on foot to all the major attractions and the Twenty one Hotel fits the job very well being just 900 mt from Vatican and 400mts from Piazza del Popolo. A 4 hour walk from there will take you to Piazza di Spagna, Pjazza Navona, Piazza Venezia, Fontana... More

Twenty One is different from the strong majority of Rome Hotels. Modern, it has all the things you expect in a hotel. But... * Do not arrive with more than one luggage. There is no available space. * Ask for a room looking for anything different from Via Cola di Rienzo. It's noisy. * Do not expect a great breakfast.... More

Modern, new hotel, well located within walking distance of the historical centre but in a quieter and more interesting area (a living neighbourhood) to reside in. Very friendly staff. Breakfast could be better but there is a lot to eat and it's included in the rate. Don't miss Gelateria die Gracchi around the corner, one of the best in town! More